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Xingang Xie

Xingang Xie
Xingang Xie
PhD、Associated Professor
Tel:
+86-13919353465
E-Mail:
xiexg@lzu.edu.cn
Mailing Address:
Room 307, The second Chemistry Building, Lanzhou University, Tianshui South Road 222#, Chengguan District, Lanzhou City, Gansu Province, P. R. China

•Education and Experience

2012-Present   College of chemistry and Chemical Engineering, Lanzhou University, 

                       State Key Laboratory of Applied Organic Chemistry, Associated Professor

2010-2012       College of chemistry and Chemical Engineering, Lanzhou University, 

                       State Key Laboratory of Applied Organic Chemistry, Lecturer

2006-2010       The Chinese University of Hong Kong (Advisor: Henry N. C. Wong), 

                       postdoctoral associate

2001-2006       Lanzhou University (Advisor: Xuegong She and Xinfu Pan), D.Sc

1997-2001       Lanzhou University, B.Sc

•Honors and Rewards

2018               Thieme Chemistry Journal Award

2015               The First Prize in Natural Science of Gansu Province (Ranking 2/5)

•Research Topics

Our group is currently interested in the development of green and sustainable organic synthetic methodology, total synthesis of bioactive natural products and structure-activity-relationship (SAR) study.  

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•Publications

1. Concise Total Syntheses of Bioactive Alkaloids Enabled by Development or Application of Cascade Reactions: a Personnel Adventure. Xingang Xie, Xuegong She*, Chinese J. Chem. 202139, 795-801.

2. Thiourea Catalyzed 1,6-Conjugate Addition of Indoles to Para-Quinone Methides. Guangmiao Wu, Tao Li, Fuhai Liu, Yulong Zhao, Shiqiang Ma, Shouchu Tang, Xingang Xie*, Xuegong She, Tetrahedron Lett2021, 81, 153315.

3. Enantioselective αFunctionalization of 1,3-Dithianes by Iridium-Catalyzed Allylic Substitution. Panpan Wang, Qian Jiang, Ruibo Zhao, Xingang Xie*. Shouchu Tang*, and Xiaolei Wang*. J. Org. Chem. 2020, 85,12456-12467.

4. Visible Light Photoredox Catalyzed Deprotection of 1,3-Oxathiolanes. Mingyang Yang, Zhimin Xing, Bowen Fang, Xingang Xie,* and Xuegong She. Org. Biomol. Chem. 2020, 18, 288-291.

5. Total syntheses of (-)-15-oxopuupehenol and (+)-puupehenone and formal syntheses of (-)-puupehenol and (+)-puupehedione, Huayue Song, Lin Liu, Mingyang Yang, Guangmiao Wu, Peng Chen, Xingang Xie * and Xuegong She, Org. Chem. Front. 20201, 35-42.

6. Synthetic studies towards daphniyunnine B: Construction of AC bicyclic skeleton with two vicinal all carbon quaternary stereocenters, Haiyu Sun, Guangmiao Wu and Xingang Xie*. Chinese Chem. Lett. 201930, 1538-1540.

7. Concise formal synthesis of (+)-pyripyropene A. Tao Li, Guangmiao Wu, Shangbiao Feng, Xiaojun Hu, Weiwei Zhang, Shouchu Tang, Xingang Xie*, Xuegong She, Tetrahedron 201975, 3939-3942.

8. Total synthesis of (-)-8-epi-chromazonarol enabled by a unique N2H4•H2O promoted intramolecular oxa-Michael cyclization reaction, Lin Liu, Huayue Song, Peng Chen, Ziyun Yuan, Shangbiao Feng, Weiwei Zhang, Bowen Fang, Xingang Xie*, Xuegong She. Org. Chem. Front. 20185, 3013-3017.

9. Visible-light promoted dithioacetalization of aldehydes with thiols under aerobic and photocatalyst-free conditions, Zhimin Xing, Mingyang Yang, Haiyu Sun, Zemin Wang, Peng Chen, Lin Liu, Xiaolei Wang, Wang*,  Xingang Xie*, Xuegong She. Green Chem. 201820, 5117-5122.

10. A rapid construction of the ABC tricyclic skeleton of malabanone A, Tao Li,  Guangmiao Wu, Shangbiao Feng, Zemin Wang, Xingang Xie*, Xuegong She.  Org. Biomol. Chem. 201816, 8491-8494.

11. Rapid construction of complex tetracyclic frameworks via a gold(I)-catalyzed tandem 1,2-acyloxy migration/[3 + 2] cycloaddition/Friedel–Crafts type cyclization reaction of linear enynyl esters. Haiyu Sun, Shiyan Xu, Zhimin Xing, Lin Liu, Shangbiao Feng, Bowen Fang, Xingang Xie*, and  Xuegong She. Org. Chem. Front20174, 2109-2113.

12. Rapid construction of the 6/6/5 tricyclic framework via a tandem radical cyclization reaction and its application to the synthesis of 5-epi-7-deoxy-isoabietenin A. Hao Zhang, Shiqiang Ma, Zhimin Xing, Lin Liu, Bowen Fang, Xingang Xie*, and Xuegong She*. Org. Chem. Front20174, 2211–2215.

13. Visible-Light-Promoted Dual C−C Bond Formations of Alkynoates via a Domino Radical  Addition/ Cyclization Reaction: A Synthesis of Coumarins. Shangbiao Feng, Xingang Xie*, Weiwei Zhang, Lin Liu, Zhuliang Zhong, Dengyu Xu, and Xuegong She.Org. Lett. 201618, 3846−3849.

14. An Efficient Synthesis of Benzazocines by Gold(I)-Catalyzed Tandem 1,2-Acyloxy Shift/[3+2] Cycloaddition of Terminal 1,9-Enynyl Esters. Shangbiao Feng, Zhengshen Wang, Weiwei Zhang, Xingang Xie*, and Xuegong She. Chem.-Asian J. 201611, 2167–2172.

15. Concise Total Synthesis of Isospongian Diterpenoid (±)-Polyrhaphin D. Zemin Wang, Zhimin Xing, Lin Liu, Hao Zhang, Zhuliang Zhong, Xingang Xie*, and Xuegong She.  ChemistrySelect 20161, 2225–2227.

16. Gold(I)-Catalyzed Tandem Reaction of γ-Amino-Substituted Propargylic Esters to Pyrrolines and its Application in the Formal Synthesis of (±)-Aphanorphine. Zhengshen Wang, Huaiji Zheng, Juan Yang, Xingang Xie*, and Xuegong She*. Adv. Synth. Catal. 2015357, 2082–2088.

17. Scalable, efficient total synthesis of (+)-mupirocin H. Changgui Zhao, Ziyun Yuan, Yuanyuan Zhang, Bin Ma, Huilin Li, Shouchu Tang, Xingang Xie* and  Xuegong She*. Org. Chem. Front. 20141, 105-108.

18. Enantioselective Total Synthesis of ()-Walsucochin B. Shiyan Xu, Jixiang Gu, Huilin Li, Donghui Ma, Xingang Xie*, and Xuegong She. Org. Lett201416, 1996-1999.

19. Concise Formal Syntheses of the Amaryllidaceae Alkaloids (±)-Tazettine and (±)-6a-Epi- pretazettine: Construction of the Core Skeleton via Tandem Intramolecular Oxidative Friedel– Crafts / Aza-Michael Reaction. Donghui Ma, Changgui Zhao, Huilin Li, Jing Qi, Ling Zhang, Shiyan Xu, Xingang Xie*, and  Xuegong She*. Chem.-Asian. J. 20138, 364-368.

20. Concise Enantioselective Synthesis of Cephalosporolide B, (4R)-4-OMe-Cephalo- sporolide C, and (4S)-4-OMe Cephalosporolide C. Bin Ma, Zhuliang Zhong, Haitao Hu, Huilin Li, Changgui Zhao, Xingang Xie*, and Xuegong She*. Chem.-Asian. J20138, 1391-1394.

21. Tandem Oxidative Dearomatization/Intramolecular Diels-Alder Reaction for Construction of the Tricyclic Core of Palhinine A. Changgui Zhao, Huaiji Zheng, Peng Jing, Bowen Fang, Xingang Xie*, and Xuegong She*. Org. Lett201214, 2293-2295.

22. Total Synthesis of (±)-Kopsihainanine A. Masaya Mizutani, Shigeo Yasuda, and  Chisato Mukai*.  Chem.-Eur. J201218, 6729-6732.

23. Rapid Construction of the [6-6-6-5] Tetracyclic Skeleton of the Daphniphyllum Alkaloid Daphenylline. Huilin Li, Jiyue Zheng, Shiyan Xu, Donghui Ma, Changgui Zhao, Bowen Fang, Xingang Xie*and Xuegong She*. Chem.-Asian. J. 20127, 2519-2522.

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