Shangwen Luo

2018-Present     College of Chemistry and Chemical Engineering, Lanzhou University，

                         State Key Laboratory of Applied Organic Chemistry, Lecturer

2016-2018         University of Illinois at Urbana-Champaign (Advisor: Satish Nair), Postdoc

2015-2016         University of Illinois at Urbana-Champaign (Advisor: Huimin Zhao), Postdoc

2010-2015         University of Illinois at Chicago (Advisor: Jimmy Orjala), PhD

2003-2010         Wuhan University, B.Sc

· Honors and Rewards

2015                  W. E. van Doren Scholarship

2013                  Graduate College Student Presenter Award

2012                  American Society of Pharmacognosy Graduate Student Travel Award

2012                  Myron Goldsmith Scholarship

· Research Interests

Natural Product Discovery from Cyanobacteria

Cyanobacteria is the only phylum of bacteria that can perform oxygenic photosynthesis. Their unique genomic context indicated that they have great potential to produce novel natural products. One of my research focus is to discover biologically active natural products form cyanobacteria for drug development.

Natural Product Biosynthesis and Enzymology

Natural products are biosynthesized by enzymatic machinery in living organisms. I am interested in deciphering biosynthetic pathways of natural products, in order to guide mass production of valuable natural products at industrial scale, and to discover novel enzymes for catalyzing reactions that are difficult to achieve by traditional catalysts.

· Selected Publications

1. Trichormamides C and D, antiproliferative cyclic lipopeptides from the cultured freshwater cyanobacterium cf. Oscillatoria sp. UIC 10045. ShangwenLuo，Hahk-SooKang，AleksejKrunic，Weilun Chen，Jilai Yang，John L.Woodard, James R.Fuchs, SangHyun Cho, Scott G.Franzblau, Steven M.Swanson, and Jimmy Orjala*. Med. Chem. 2015, 23, 3153-3162.

2. Microseiramide from the freshwater cyanobacterium Microseira sp. UIC 10445. Shangwen Luo, AleksejKrunic, George E.Chlipala, and JimmyOrjala*. Phytochemistry Lett. 2015, 13, 47-52.

3. Trichormamides A and B with antiproliferative activity from the cultured freshwater cyanobacterium Trichormus.  Shangwen Luo, Aleksej Krunic, Hahk-Soo Kang, Weilun Chen, John L Woodard, James R Fuchs , Steven M Swanson, Jimmy Orjala. J. Nat. Prod. 2014, 77, 1871-1880.

4. Carbamidocyclophanes F and G with anti-Mycobacterium tuberculosis activity from the cultured freshwater cyanobacterium Nostoc sp.  ShangwenLuo, Hahk-SooKang, AleksejKrunic, George E.Chlipala, GepingCai, Weilun Chen, Scott G.Franzblau, Steven M.Swanson, and JimmyOrjala*. Tetrahedron Lett. 2014, 55, 686-689.