•Education and Experience
2016 - Present State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
Professor
2008-2016 State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
Associate Professor
2005-2008 State Key Laboratory of Applied Organic Chemistry, Lanzhou University,
Lecturer
2009-2010 University of California, Santa Cruz (Advisor: Phillip Crews), Postdoc
2002-2005 Lanzhou University, Ph.D.
1999-2002 Lanzhou University, M.S.
1995-1999 Lanzhou University, B.S.
•Research Topics
1. The structure and activity of the secondary metabolite from the microorganism derived from the plant, insect, and soil.
2. The structure and activity of the secondary metabolite from the medicinal plant.
3. The drug and health care product from the plant and microorganism.
•Publications
1. Alterperylenol as a Novel Thioredoxin Reductase Inhibitor Induces Liver Cancer Cell Apoptosis and Ferroptosis. Junmin Xi, Li-Li Tian, Jiahui Xi, Desire Girimpuhwe, Chongfei Huang, Ruixia Ma, Xiaojun Yao, Danfeng Shi, Zhongtian Bai*, Quan-Xiang Wu*, and Jianguo Fang*, J. Agric. Food Chem. 2022, 70,15763-15775.
2. Indole alkaloids from a soil-derived Clonostachys rosea. Chun-Xiao Jiang, Bo Yu, Ya-Mei Miao, Hao Ren, Qianhe Xu, Chun Zhao, Li-Li Tian, Zhen-Qing Yu, Pan-Pan Zhou, Xiaolei Wang, Jianguo Fang, Jiwen Zhang, Jin Z. Zhang, Quan-Xiang Wu*. J. Nat. Prod. 2021, 84, 2468−2474.
3. Activation of cellular antioxidant defense system by naturally occurring dibenzopyrone derivatives confers neuroprotection against oxidative insults. Yanan Hou, Jie Li, Jun-Chen Wu, Quan-Xiang Wu*, Jianguo Fang*. ACS Chem. Neurosci. 2021, 12, 2798−2809.
4. Diverse anti-inflammation and anti-cancer polyketides isolated from the endophytic fungi Alternaria sp. MG1. Li-Li Tian, Hao Ren, Jun-Min Xi, Jianguo Fang, Jin Z. Zhang, Quan-Xiang Wu*. Fitoterapia 2021, 153, 105000.
5. (±)-Alternamgin, a pair of enantiomeric polyketides, from the endophytic fungi Alternaria sp. MG1. Junchen Wu, Yanan Hou, Qian Xu, Xiaojie Jin, Yaxiong Chen, Jianguo Fang, Burong Hu, and Quanxiang Wu*. Org. Lett. 2019, 21, 1551–1554.
6. Isolation, identification, and activity evaluation of chemical constituents from soil fungus Fusarium avenaceum SF-1502 and endophytic fungus Fusarium proliferatum AF-04. Chunxiao Jiang, Jie Li, Junmin Zhang, Xiaojie Jin, Bo Yu, Jianguo Fang, and Quanxiang Wu*. J. Agr. Food Chem. 2019, 67, 1839-1846.
7. Two novel bioactive sulfated guaiane sesquiterpenoid salt alkaloids from the aerial parts of Scorzonera divaricate. Quanxiang Wu, Xiaofeng He, Chunxiao Jiang, Wei Zhang, Zhuanning Shi, Hongfang Li, and Ying Zhu. Fitoterapia 2018, 124, 113-119.
8. Sesquiterpenes and diterpenes with cytotoxic activities from the aerial parts of Carpesium humile. Dongdong Xu, Yuan Yan, Chunxiao Jiang, Jingjing Liang, Hongfang Li, Quanxiang Wu, and Ying Zhu. Fitoterapia 2018, 128, 50–54.
9. Isolation of Secondary Metabolites from the Soil-Derived Fungus Clonostachys rosea YRS-06, a Biological Control Agent, and Evaluation of Antibacterial Activity. Mingming Zhai, Fengming Qi, Jie Li, Chunxiao Jiang, Yue Hou, Yanping Shi, Duolong Di, Ji-Wen Zhang, and Quanxiang Wu*. J. Agr. Food Chem. 2016, 64, 2298–2306.
10. Talaromycolides A–C, Novel Phenyl-Substituted Phthalides Isolated from the Green Chinese Onion-Derived Fungus Talaromyces pinophilus AF-02. Mingming Zhai, Haitao Niu, Jie Li, Hui Xiao, Yanping Shi, Duolong Di, Phillip Crews, and Quanxiang Wu*. J. Agr. Food Chem. 2015, 63, 9558–9564.
11. Pyrone Derivatives from the Endophytic Fungus Alternaria tenuissima SP-07 of Chinese Herbal Medicine Salvia przewalskii. Xiaozheng Wang, Xiaohong Luo, Jie Xiao, Mingming Zhai, Yun Yuan, Ying Zhu, PhillipCrews, Chengshan Yuan, and Quanxiang Wu*. Fitoterapia 2014, 99, 184–190.
12. New Abietane Diterpenoids from the Roots of Salvia przewalskii. J Hailong Jiang, Xiaozheng Wang, Jie Xiao, Xiaohong Luo, Xiaojun Yao, Yuanyuan Zhao, Yongjia Chen, PhillipCrews, and Quanxiang Wu*. Tetrahedron 2013, 69, 6687–6692.
13. New Isocoumarins and Alkaloid from Chinese Insect Medicine, Eupolyphaga sinensis Walker. Hailong Jiang, Xiaohong Luo, Xiaozheng Wang, Junli Yang, Xiaojun Yao, PhillipCrews, Frederick A.Valeriote, and Quan-XiangWu*. Fitoterapia 2012, 83, 1275-1280.
14. The Biosynthetic Products of Chinese Insect Medicine, Aspongopus chinensis. Xiaohong Luo, Xiaozheng Wang, Hailong Jiang, Junli Yang, PhillipCrews, Frederick A.Valeriote, Quan-XiangWu*. Fitoterapia 2012, 83, 754–758.
15. Unraveling the Numerous Biosynthetic Products of the Marine Sediment-Derived Fungus, Aspergillus insulicola. Wu, Q.-X.; Jin, X.-J.; Draskovic, M.; Crews, M.S.; Tenney, K.; Valeriote, F.A.; Yao, X.-J.; Crews, P.* Phytochem. Lett. 2012, 5, 114–117.
16. Sesquiterpenoids, Alantolactone Analogues, and Seco-Guaiene from the Roots of Inula helenium. Hailong Jiang, Jia Chen, Xiaojie Jin, Junli Yang, Ya Li, Xiaojun Yao*, and Quanxiang Wu*. Tetrahedron 2011, 67, 9193–9198.
17. Triterpenes and Steroids from the Roots of Scorzonera austriaca. Quanxiang Wu,Yibin Su,and Ying Zhu*.Fitoterapia 2011, 82, 493–496.
18. Azonazine, a Novel Dipeptide from a Hawaiian Marine Sediment-Derived Fungus, Aspergillus insulicola. Quanxiang Wu, Mitchell S. Crews, Marija Draskovic, Johann Sohn, Tyler A. Johnson, Karen Tenney, Frederick A. Valeriote, Xiao-Jun Yao, Leonard F. Bjeldanes, and Phillip Crews*. Org. Lett. 2010, 12, 4458–4461.
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