2003-present Professor, State Key Laboratory of Applied Organic Chemistry,
College of Chemistry and Chemical Engineering, Lanzhou University
2018-2022 Dean of Office of Scientific research and Development, Lanzhou University
2015-2018 Executive Director of Cuiying Honors College, Lanzhou University
2009-2015 Director of the Department of academic Affairs, Lanzhou University
2003-2004 Visiting Professor of International Research Center for Materials and
Materials Science, Nagoya University (Advisor: Prof. K. Tatsumi)
1999-2001 Postdoc, National Chung Hsing University,Taiwan (Prof. Lu Darong)
1996-1998 D. S., Lanzhou University (Advisor: Prof. Zhang Ziyi)
1992-1994 M. S., Lanzhou University (Advisor: Prof. Wu Shaozu)
1983-1987 B. S., Department of Organic Chemistry, Lanzhou University (Advisor: Prof. Li Yu)
· Honors & Awards
2019 Gansu Provincial Natural Science Award (2nd Prize)
2016 Guohua Outstanding Scholar of Lanzhou University
2014 National Excellent Tutor, Baosteel Education Award
2014 First Prize, Science and Technology Progress Award of Gansu Province
( first author)
2013 Model of Education Ethics of the University; Individual Pacemaker of
Teaching Ethics of the Province
2012 First Prize of Science and Technology Progress, Jinchuan Group; Special
government allowances of the State Council
2010 First Prize, Natural Sciences Award of the Province (lead author)
2009 Selection as one of the provincial leading academics;
Thieme Chemistry Journal Award
2005 Inclusion in Program for New Century Excellent Talents in University,
Ministry of Education; Incorporation in Project 555 of Innovative Talents,
Gansu Province
2002 The 9th Accomplished Young Tutor of Gansu Province; Third Prize(two pieces),
Science and Technology Progress Award of Gansu Province
Research Interests:
1) Asymmetric synthesis and methods of α-amino acids
2) Organocatalytic asymmetric cascade reactions
3) Organocatalyzed reactions guided by natural products structure
4) Visible-light catalyzed organic reactions
5) Design and application of novel Photosensitizer
6) Development of novel flotation agents
· Publications:
1. A Novel Approach for Synthesizing α-amino Acids via Formate Mediated Hydrogen Transfer using a Carbon Source. Tian-Tian Zhao‡, Xu-Gang Zhang‡, Wen-Bo He and Peng-Fei Xu *, Green Commun., 2023, 25, 8539.
2. Organic Photoredox Catalyzed Dealkylation/Acylation of Tertiary Amines to Access Amides. Chen Liu‡, Han-Nan Chen‡, Teng-Fei Xiao, Xiu-Qin Hu*, Peng-Fei Xu, and Guo-Qiang Xu*, Chem. Commun., 2023, 59, 2003.
3. Light-Promoted Nickel-Catalyzed C-O/C-N Coupling of Aryl Halides with Carboxylic Acids and Sulfonamides. Tian-Tian Zhao, Hao-Ni Qin, and Peng-Fei Xu*, Org. Lett., 2023, 25, 636.
4. Pcet-Mediated Ring-Opening Alkenylation of Cycloalkanols via Dual Photoredox and Cobalt Catalysis. Zi-Gang Ren, Wan-Lei Yu, Hai-Xue Zheng, and Peng-Fei Xu*, Org. Lett., 2023, 25, 93.
5.Solvent Directed Chemically Divergent Synthesis of β-lactams and α-amino Acid Derivatives With Chiral Isothiourea. Dong-Sheng Ji, Hui Liang, Kai-Xuan Yang, Zhi-Tao Feng, Yong-Chun Luo*, Guo-Qiang Xu, Yucheng Gu, and Peng-Fei Xu*, Chem. Sci. 2022, 13, 1801.
6.Cobalt-catalyzed Chemoselective Dehydrogenation Through Radical Translocation Under Visible Light. Wan-Lei Yu, Zi-Gang Ren, Ke-Xing Ma, Hui-Qing Yang, Jun-Jie Yang, Haixue Zheng*, Wangsuo Wu, and Peng-Fei Xu*, Chem. Sci. 2022, 13, 7947.
7. Organophotoredox Catalytic four-component Radical-polar Crossover Cascade Reactions for the Stereoselective Synthesis of β-amido Sulfones. Sheng-Qiang Guo, Hui-Qing Yang, Yu-Zhen Jiang, Ai-Lian Wang, Guo-Qiang Xu, Yong-Chun Luo, Zhao-Xu Chen, Haixue Zheng*, and Peng-Fei Xu*, Green Chem. 2022, 24, 3120.
8. Photoredox/Nickel Dual Catalyzed Stereospecific Synthesis of Distal Alkenyl Ketones. Tian-Tian Zhao, Wan-Lei Yu, Zhi-Tao Feng, Hao-Ni Qin, Haixue Zheng*, and Peng-Fei Xu*, Chem. Commun. 2022, 58, 1171.
9. Organocatalytic Inverse-Electron-Demand Diels-Alder Reaction Between 5-alkenyl Thiazolones and β,γ-Unsaturated Carbonyl Compounds. Kai-Xuan Yang, Dong-Sheng Ji, Haixue Zheng, Yucheng Gu*, and Peng-Fei Xu*, Chem. Commun. 2022, 58, 4227.
10. Divergent Ritter-type Amination via Photoredoxcatalytic Four-Component Radical-Polar Crossover Reactions. Sheng-Qiang Guo, Hui-Qing Yang, Ai-Lian Wang, Yu-Zhen Jiang, Guo-Qiang Xu, Yong-Chun Luo*, Zhao-Xu Chen, Peng-Fei Xu*, Green Chem. 2021, 23, 9571-9576.
11. Visible-Light Induced Generation of Bifunctional Nitrogen-Centered Radicals: A Concise Synthetic Strategy to Construct Bicyclo-[3.2.1]octane and Azepane Cores. Wanlei Yu, Haowen Jiang, Lei Yan, Zhitao Feng, Yongchun Luo, Pengfei Xu*. Sci. China Chem. 2021, 64, 274-280.
12. Photoredox Catalyzed Hydrocarboxymethylation of Alkenes. Jie Fang, Qiang Hu, Wanli Dong, Guoqiang Xu, Xiuqin Hu, Yongchun Luo, and Pengfei Xu*. CCS Chem. 2021, 43, 95-104.
13. Highly Enantioselective Construction of Strained Spiro[2,3]hexanes via Michael-Ring Expansion-Cyclization Cascade Strategy. Chuangang Zhao, Zhitao Feng, Guoqiang Xu*, Ang Gao, Jingwei Chen, Zhuyin Wang, and Pengfei Xu*. Angew. Chem. Int. Ed. 2020, 59, 3058-3062.
14. A lutidine-promoted photoredox catalytic atom-transfer radical cyclization reaction for the synthesis of 4-bromo-3,3-dialkyl-octahydroindol-2-ones. Quansheng Zhao, Guoqiang Xu, Jitao Xu, Zhuyin Wang, and Pengfei Xu*. Chem. Commun. 2020, 56, 2206-2209.
15. Enantioselective Synthesis of Spirorhodanine-Pyran Derivatives via Organocatalytic [3+3] Annulation Reactions between Pyrazolones and Rhodanine-Derived Ketoesters. Dongsheng Ji, Yongchun Luo, Xiuqin Hu, and Pengfei Xu*. Org. Lett. 2020, 22, 1028−1033.
16. Asymmetric Organocatalytic [4+1] Annulations Involving a Polarity Reversal Process: A Tandem Catalytic Approach to Highly Functionalized piropyrazolone Derivatives. Changyin Tan, Hong Lu, Jialu Zhang, Jinyu Liu, and Pengfei Xu*. J. Org. Chem. 2020, 85, 594−602.
17. Dehydrogenative Silylation of Alkenes for the Synthesis of Substituted Allylsilanes by Photoredox, Hydrogen-Atom Transfer, and Cobalt Catalysis. Wanlei Yu, Yongchun Luo, Lei Yan, Dan Liu, Zhuyin Wang, and Pengfei Xu*.Angew. Chem. Int. Ed. 2019, 58, 10941.
18. Ni-Catalyzed 1,2-Acyl Migration Reactions Triggered by C–C Bond Activation of Ketones. Cheng Jiang, Hong Lu, Wenhua Xu, Jianing Wu, Tianyang Yu, Pengfei Xu, and Hao Wei*. ACS Catal. 2019, 10, 1947-1975.
19. Photocatalyzed Metal-Free Alkylheteroarylation of Unactivated Olefins via Direct Acidic C(sp3)−H Bond Activation. Jie Fang, Wanli Dong, Guoqiang Xu, and Pengfei Xu*. Org. Lett. 2019, 21, 4480−4485.
20. Metal-Free Visible-Light-Induced Construction of Difluoro- Containing Dibenzazepines. Dan Liu, Mengjie Jiao, Xingzhi Wang, and Pengfei Xu*.Org. Lett. 2019, 21, 4745.
21. An Atropo-enantioselective Synthesis of Benzo-Linked Axially Chiral Indoles via Hydrogen-Bond Catalysis. Jinyu Liu, Xiechao Yang, Zhen Liu, Yongchun Luo, Hong Lu, Yucheng Gu, Ran Fang, and Pengfei Xu*.Org. Lett. 2019, 21, 5219.
22. Aroylchlorination of 1,6-Dienes via a Photoredox Catalytic Atom-Transfer Radical Cyclization Process. Quansheng Zhao, Guoqiang Xu, Hui Liang, Zhuyin Wang, and Pengfei Xu*. Org. Lett. 2019, 21, 8615.
23. Synthesis of indolo[2,1-a]isoquinoline derivatives via visible-light-induced radical cascade cyclization reactions. Yunlong Wei, Jianqiang Chen, Bo Sun, and Pengfei Xu*. Chem. Commun. 2019, 55, 5922.
24. Directed Decarbonylation of Unstrained Aryl Ketones via Nickel-Catalyzed C-C Bond Cleavage. Tiantian Zhao, Wen-Hua Xu, Zhaojing Zheng, Pengfei Xu*, and Hao Wei*. J. Am. Chem. Soc. 2018, 140, 586.
25. Dual Csp3-H Bond Functionalization of N-Heterocycles via Visible-Light Photocatalyzed Dehydrogenation /[2+2] Cycloaddition Sequential Reaction. Guoqiang Xu, Jitao Xu, Zhitao Feng, Hui Liang, Zhuyin Wang, Yong Qin, and Pengfei Xu*. Angew. Chem. Int. Ed. 2018, 57, 5110.
26. Organocatalytic, Enantioselective Friedel−Crafts Reaction of Indoles in the Carbocyclic Ring and Electron-Rich Phenols. Jinyu Liu, Xiechao Yang, Hong Lu, Yucheng Gu, and Pengfei Xu*. Org. Lett. 2018, 20, 2190.
27. Photoredox-Induced Intramolecular 1,5‑H Transfer Reaction of Aryl Iodides for the Synthesis of Spirocyclic γ‑Lactams. Jianqiang Chen, Rui Chang, Junbing Lin, Yongchun Luo, and Pengfei Xu*. Org. Lett. 2018, 20, 2395.
28. Regiospecific Three-Component Aminofluorination of Olefins via Photoredox Catalysis. Jianan Mo, Wanlei Yu, Jianqiang Chen, Xiuqin Hu*, and Pengfei Xu*. Org. Lett. 2018, 20, 4471.
29. Design, Synthesis, and Application of Highly Reducing Organic Visible-Light Photocatalysts. Liu Dan, Jiao Mengjie, Feng Zhitao, Wang Xingzhi, Xu Guoqiang, and Xu Pengfei*. Org. Lett. 2018, 20, 5700.
30. Dearomative Dienolate-Mediated Catalysis: A Remote Activation Strategy for Asymmetric Functionalization of Benzylic C−H Bonds of Heteroaryl Aldehydes. Yang Wang, Junbing Lin, Jikang Xie, Hong Lu, Xiuqin Hu, and Pengfei Xu*.Org. Lett. 2018, 20, 5835.
31. Alkene functionalization for the stereospecific synthesis of substituted aziridines by visible-light photoredox catalysis. Wanlei Yu, Jianqiang Chen, Yunlong Wei, Zhuyin Wang, and Pengfei Xu*. Chem. Commun. 2018, 54, 1948-1951.
32. A new approach to access difluoroalkylated diarylmethanes via visible-light photocatalytic cross-coupling reactions. Zhao Yinna, Luo Yongchun, Wang Zhuyin, and Xu Pengfei*. Chem. Commun. 2018, 54, 3993.
33. Synthesis of five-membered cyclic nitrones based on the Lewis acid-catalysed [3+2]-annulation reaction of donor–acceptor cyclopropanes with 1,4,2-dioxazoles. Xu Pengfei*, Zhang Huanhuan, Luo Yongchun, Wang Zhehao. Chem. Commun. 2018, 54, 10128.
34. N‑Heterocyclic Carbene-Catalyzed Atom-Economical and Enantioselective Construction of the C−S Bond: Asymmetric Synthesis of Functionalized Thiochromans. Hong Lu, Jialu Zhang, Jinyu Liu, Hongyu Li, and Pengfei Xu*. ACS Catal. 2017, 7, 7797.
35. 3,4,5-Trimethylphenol and Lewis Acid Dual-Catalyzed Cascade Ring-Opening/Cyclization: Direct Synthesis of Naphthalenes. Ma He, Hu Xiuqin, and Xu Pengfei*, Luo Yongchun. Org. Lett. 2017, 19, 6666.
36. Visible-Light-Induced Aza-Pinacol Rearrangement: Ring Expansion of Alkylidenecyclopropanes. Wendeng Liu, Guoqiang Xu, Xiuqin Hu, and Pengfei Xu*. Org. Lett. 2017, 19, 6291.
37. Highly Enantioselective Construction of Hajos-Wiechert Ketone Skeletons via an Organocatalytic Vinylogous Michael/Stetter Relay Sequence. Zhilong Jia, Yao Wang, Chuangang Zhao, Xiaohai Zhang, and Pengfei Xu*.Org. Lett. 2017, 19, 2130.
38. Quaternary Carbon Center Forming Formal [3+3] Cycloaddition Reaction via Bifunctional Catalysis: Asymmetric Synthesis of Spirocyclohexene Pyrazolones. Jinyu Liu, Jing Zhao, Jialu Zhang, and Pengfei Xu*. Org. Lett. 2017, 19, 1846.
39. Synthesis of Fused Pyran Derivatives via Visible-Light-Induced Cascade Cyclization of 1,7-Enynes with Acyl Chlorides. Chenguang Li , Guoqiang Xu, and Pengfei Xu*, Org. Lett. 2017, 19, 512.
40. Rh(II) Catalyzed High Order Cycloadditions of 8-Azaheptafulvenes with N-Sulfonyl 1,2,3-Triazloes or α-Oxo Diazocompounds. Wei Chen, Yali Bai , Yongchun Luo , Pengfei Xu*. Org. Lett. 2017, 19, 364.
41. Lewis acid catalyzed diastereoselective [3+4]-annulation of donor-acceptor cyclopropanes with anthranils: synthesis of tetrahydro-1-benzazepine derivatives. Zhehao Wang, Huanhuan Zhang*, Daoming Wang, Pengfei Xu, and Yongchun Luo*. Chem. Commun. 2017, 53, 8521.
42. Kinetic resolution via supramolecular iminium catalysis: multiactivation enables the asymmetric synthesis of β-aryl substituted aldehydes and densely functionalized cyclohexanes. Zhilong Jia, Yao Wang*, Guoqiang Xua, and Pengfei Xu*. Chem. Commun. 2017, 53, 4938.
43. Asymmetric Catalytic Cascade Reactions for Constructing Diverse Scaffolds and Complex Molecules. Yao Wang, Hong Lu, and Pengfei Xu*. Acc. Chem. Res. 2015, 48, 1832.
44. Catalytic Cascade Reactions. Pengfei Xu, and Wei Wang. 2014,DOI:10.1002/9781118356654.
45. Rationally Designed Multifunctional Supramolecular Iminium Catalysis: Direct Vinylogous Michael Addition of Unmodified Linear Dienol Substrates. Yun Gu, Yao Wang, Tianyang Yu, Yongmin Liang, Pengfei Xu*. Angew. Chem. Int. Ed. 2014, 53, 14128.
46. Hydrogen-Bond-Mediated Supramolecular Iminium Ion Catalysis. Yao Wang, Tianyang Yu，Hongbo Zhang, Yongchun Luo, Pengfei Xu*. Angew. Chem. Int. Ed. 2012, 51, 12339.
47. Synthesis of a-Amino Acids Based on Chiral Tricycloiminolactone Derived from Natural (+)-Camphor. Yongchun Luo, Huanhuan Zhang, Yao Wang, and Pengfei Xu*. Acc. Chem. Res. 2010, 43, 1317.
48. Asymmetric Organocatalytic Relay Cascades: Catalyst-Controlled Stereoisomer Selection in the Synthesis of Functionalized Cyclohexanes. Yao Wang, Ronggang Han, Yonglong Zhao, Shu Yang, Pengfei Xu*, and Darren J. Dixon*. Angew. Chem. Int. Ed. 2009, 48, 9834.
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