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张晓明

张晓明
张晓明
博士、副教授、硕士生导师
电话:
+86-13893106341
邮箱:
zhangxiaom@lzu.edu.cn
·教育背景、工作经历

2021-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室,副教授

2013-2020           兰州大学化学化工学院、功能有机分子化学国家重点实验室,讲师

2007-2013           兰州大学化学化工学院 (导师: 涂永强院士),理学博士

2003-2007           兰州大学化学化工学院基地班,理学学士

•荣誉奖励

2020                 本科毕业论文优秀指导教师

2013                 国家奖学金

2011                 博士研究生学术新人奖

研究兴趣

活性天然产物全合成

不对称催化合成方法学

•代表成果

1. Catalytic Asymmetric Polycyclization of Tertiary Enamides with Silyl Enol Ethers: Total Synthesis of (–)-Cephalocyclidin A. Qing-Bo Zhuang, Jin-Rui Tian, Ka Lu, Xiao-Ming Zhang*, Fu-Min Zhang, Yong-Qiang Tu*, Rong Fan, Zhi-Hao Li, and Yu-Dong Zhang, J. Am. Chem. Soc.  2023, 145, 26550.

2. Photoinduced Reductive Reformatsky Reaction of Α-Haloesters and Aldehydes or Ketones by Cooperative Dual-Metal Catalysis. Qi-Long Chen, Le Mao, Yi-Fan Pan, Heng Cai, Xiao-Ming Zhang*, Fu-Min Zhang, Ai-Jun Ma, Jin-Bao Peng, and Yong-Qiang Tu, Chem. Commun. 2023, 59, 14427.

3. Catalytic Enantioselective Alkylation of Aldehydes with 3‑Bromooxindoles. Zhen Li, Xiao-Ming Zhang*, Fu-Min Zhang, and Yong-Qiang Tu, Org. Lett. 2023, 25, 7252.

4. Catalytic Enantioselective Steglich-Type Rearrangement of Enol Lactones: Asymmetric Synthesis of Spirocyclic 1,3-Diketones. Xiao-Yan Zhang, Ka Lu, Bao-Kuan Guo, Ya-Ping Shao, Hong Wang, Fu-Min Zhang, Yong-Qiang Tu, and Xiao-Ming Zhang*, J. Org. Chem. 2022, 87,15031.

5. Recent Development and Applications of Semipinacol Rearrangement Reactions. Xiao-Ming Zhang,Bao-Sheng Li*, Shao-Hua Wang*, Kun Zhang, Fu-Min Zhang, and Yong-Qiang Tu,Chem. Sci. 2021, 12, 9262–9274.

6. Catalytic Enantioselective Synthesis of Chiral Spirocyclic 1,3-Diketones via Organo-Cation Catalysis. Xiao-Yan Zhang, Ya-Ping Shao, Bao-Kuan Guo, Kun Zhang, Fu-Min Zhang, Xiao-Ming Zhang*, and Yong-Qiang Tu*, Chem. Commun202157, 11233-11235.

7. Collective Total Synthesis of Aspidofractinine Alkaloids through the Development of a Bischler–Napieralski/Semipinacol Rearrangement Reaction. Wang, S.-H.; Si, R.-Q.; Zhuang, Q.-B.; Guo, X.; Ke, T.; Zhang, X.-M.;* Zhang, F.-M.;* Tu, Y.-Q.* Angew. Chem., Int. Ed. 2020, 59, 21954-21958.

8. Allylic Arylation of 1,3-Dienes via Hydroboration/Migrative Suzuki–Miyaura Cross-Coupling Reactions. Xiaoming Zhang*, Jie Yang, Qingbo Zhuang, Yongqiang Tu, Zongyuan Chen, Hui Shao, Shaohua Wang, and Fumin Zhang. ACS Catal. 2018, 8, 6094-6099.

9. A Catalytic Allylic Cation-Induced Intermolecular Allylation-Semipinacol Rearrangement. Minghui Xu, Kunlong Dai, Yongqiang Tu*, Xiaoming Zhang*, Fumin Zhang, and  Shao-Hua Wang. Chem. Commun. 2018, 54, 7685-7688.

10. Tandem SN2′ nucleophilic substitution/oxidative radical cyclization of aryl substituted allylic alcohols with 1,3-dicarbonyl compounds. Zhen Zhang, Cheng Li, Shaohua Wang, Fumin Zhang, Xue Han, Yongtiang Tu*, and  Xiaoming Zhang*. Org. Biomol. Chem. 2017, 15, 3239–3247.

11. Recent Applications of the 1,2-Carbon Atom Migration Strategy in Complex Natural Product Total Synthesis. Xiaoming Zhang, Yongqiang Tu*, Fumin Zhang, Zhihua Chen, and Shaohua Wang*. Chem. Soc. Rev. 201746, 2272-2305.

12. Radical Aryl Migration Reactions and Synthetic Applications. Zhimin Chen#, Xiaoming Zhang#, and Yongqiang Tu*. Chem. Soc. Rev. 201544, 5220-5245. (# equal contribution)

13. Total Synthesis of (+)-Alopecuridine, (+)-Sieboldine A, and (-)-Lycojapodine A. Xiaoming Zhang, Hui Shao, Yongqiang Tu*, Fumin Zhang, and Shaohua Wang*. J. Org. Chem. 201277, 8174−8181.

14. Total Synthesis of (±)-Alopecuridine and Its Biomimetic Transformation into (±)-Sieboldine A. Xiaoming Zhang, Yongqiang Tu*, Fumin Zhang, Hui Shao, and Xing Meng. Angew. Chem. Int. Ed. 201150, 3916 –3919.

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