李辉林
2023.06-至今 兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授
2018.06-2023.06 兰州大学化学化工学院、功能有机分子化学国家重点实验室,青年研究员
2016.11-2018.06 新加坡国立大学化学系 (导师:卢一新教授),博士后
2015.06-2016.10 香港科技大学化学系 (导师:孙建伟教授),博士后
2010.09-2015.06 兰州大学 (导师: 厍学功),理学博士
2006.09-2010.06 兰州大学,理学学士
·研究兴趣
天然产物全合成,天然产物结构导向的方法学研究,不对称催化等
·代表成果
1. Total Synthesis of the Euphorbia Diterpenoid Pepluacetal. Meng Liu, Chuanhua Wu, Xingang Xie,Huilin Li*, and Xuegong She*, Angew. Chem. Int. Ed., 2024, e202400943.
2. Rearrangement of the Tetra- and Tricyclic Skeletons of Pepluanol B to Access the Core Structures of Tigliane- and Myrsinane-Type Euphorbia Diterpenes. Chuanhua Wu, Jing Zhang, Meng Liu, Xingang Xie, Huilin Li*, and Xuegong She*, Org. Lett., 2023, 25, 7995.
3. Catalyst-Free 1,2-Dibromination of Alkenes Using 1,3-Dibromo-5,5-dimethylhydantoin (DBDMH) as a Bromine Source. Lei Wang, Lele Zhai, Jinyan Chen, Yulin Gong, Peng Wang, Huilin Li*, and Xuegong She, J. Org. Chem. 2022, 87, 3177.
4. Solvent-free, B(C6F5)3-Catalyzed S-H Insertion of Thiophenols and Thiols with α-Diazoesters. Peng Wang, Yulin Gong, Xiaoyu Wang, Yangqing Ren, Lei Wang, Lele Zhai, Huilin Li* and Xuegong She, Chem - Asian J. 2022, 17, e202200465.
5. Organoborane-Catalyzed Selective 1,2-Reduction of Alkynones with Hydride Transfer: Synthesis of Benzyl Alkynes. Lele Zhai, Zhigang Yang, Qinghong Man, Mingyu Yang, Yangqing Ren, Lei Wang, Huilin Li*, and Xuegong She, Tetrahedron Lett. 2022, 91, 153645.
6. The Total Synthesis of Diquinane-Containing Natural Products. Huilin Li*, Jing Zhang, and Xuegong She*, Chem-Eur. J. 2021, 27, 4839-4858.
6. Recent Advances in Total Synthesis of Diquinane-Containing Natural Products, Huilin Li*, Jing Zhang, Xuegong She*. Chem.-Eur. J. 2021, 27, 1-21.
8. Total Synthesis of (-)-Pepluanol B: Conformational Control of the Eight-Membered Ring System, Jing Zhang, Meng Liu, Chuanhua Wu, Gaoyuan Zhao, Peiqi Chen, Lin Zhou, Xingang Xie, Ran Fang, Huilin Li*, and Xuegong She*. Angew. Chem. Int. Ed. 2020, 59, 3966-3970.
9. Total Synthesis of (−)-Gardmultimine A,Peiqi Chen, Hesi Yang, Hao Zhang, Wei Chen, Zheng Zhang, Jing Zhang, Huilin Li, Xiaolei Wang, Xingang Xie, and Xuegong She*. Org. Lett. 2020, 22, 2022–2025.
10. A Strategy to Construct cis-Hydrocarbazole via Nickel/Lewis Acid Dual-Catalyzed Arylcyanation, Hao Zhang, Peiqi Chen, Hesi Yang, Shiqiang Ma, Zemin Wang, Xingang Xie, Xiaolei Wang, Huilin Li, and Xuegong She*. J. Org. Chem. 2020, 85, 3954–3962.
11. Synthesis of 2,3-disubstituted indoles via a tandem reaction, Shiqiang Ma, Dan Long, Peiqi Chen, Hongliang Shi, Huilin Li, Ran Fang, Xiaolei Wang, Xingang Xie , and Xuegong She*. Org. Chem. Front. 2020, 7, 2689-2695.
12. A copper-catalyzed radical coupling/fragmentation reaction: efficient access to β-oxophosphine oxides,Shangbiao Feng, Jinlai Li, Feifei He, Tao Li, Huilin Li, Xiaolei Wang, Xingang Xie, and Xuegong She*. Org. Chem. Front. 2019, 6, 946-951.
13. A concise approach to the tricyclic framework of longipinane- and ent-longipinane-type sesquiterpenoids, Min He, Jiuzhou Yi, Gaoyuan Zhao, Peiqi Chen, Dan Long, Xiaojun Hu, Huilin Li,Xingang Xie, Xiaolei Wang, and Xuegong She*. Org. Chem. Front. 2019, 6, 383-387.
14. Total Synthesis of Aspidofractinine Alkaloid Paucidirinine, Weiwei Zhang, Shanhao Lin, Chenglong Du, Shangbiao Feng, Zaimin Liu, Jing Zhang, Xingang Xie, Xiaolei Wang, Huilin Li, and Xuegong She*. J. Org. Chem. 2019, 84, 1111-1116.
15. Asymmetric Total Synthesis of (+)-Winchinine B, Zaimin Liu, Xiaolin Ju, Shiqiang Ma, Chenglong Du, Weiwei Zhang, Huilin Li, Xiaolei Wang, Xingang Xie, and Xuegong She*. J. Org. Chem. 2019, 84, 14994-15000.
16. Construction of the Tetracyclic Core of Calyciphylline B‑Type Daphniphyllum Alkaloids, Chenglong Du, Jing Fang, Jinyan Chen, Zaimin Liu, Huilin Li, Xiaolei Wang, Xingang Xie, and Xuegong She*, Org. Lett. 2019, 21, 8718−8721.
17. Bioinspired total synthesis of (−)-gymnothelignan L. Peng Chen, Liang Huo, Huilin Li, Lin Liu, Ziyun Yuan, Hao Zhang, Shangbiao Feng, Xingang Xie, Xiaolei Wang, and Xuegong She*. Org. Chem. Front. 2018, 5, 1124-1128.
18. Enantioselective Construction of All‐Carbon Quaternary Stereogenic Centers by Using Phosphine Catalysis. Huilin Li, and Yixin Lu*. Asian. J. Org. Chem. 2017, 6, 1130-1145.
19. Catalytic Enantioselective Aza‐Piancatelli Rearrangement. Huilin Li,Rongbiao Tong,and Jianwei Sun*. Angew. Chem. Int. Ed. 2016, 55, 15125-15128.
20. Bioinspired Total Synthesis of Gymnothelignan N. Huilin Li, Yuanyuan Zhang, Xingang Xie, Haichen Ma, Changgui Zhao, Gaoyuan Zhao, and Xuegong She*. Org. Lett. 2014, 16, 4440-4443.
21. Diels–Alder/Oxidative Aromatization Approach towards the All‐Carbon DEF Tricyclic Skeleton of Daphenylline. Huilin Li, Yangcheng Qiu, Changgui Zhao, Ziyun Yuan, Xingang Xie, and Xuegong She*. Chem.-Asian J. 2014, 9, 1274-1277.
22. Rapid Construction of the [6‐6‐6‐5] Tetracyclic Skeleton of the Daphniphyllum Alkaloid Daphenylline. Huilin Li, Jiyue Zheng, Shiyan Xu, Donghui Ma, Changgui Zhao, Bowen Fang, Xingang Xie*, and Xuegong She*. Chem.-Asian J. 2012, 7, 2519-2522.