陈小明
2024-至今 兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授
2019-2024 兰州大学化学化工学院、功能有机分子化学国家重点实验室,青年研究员
2017-2019 北京大学深圳研究生院,助理研究员
2015-2017 北京大学深圳研究生院 (导师: 翟宏斌),博士后
2009-2015 兰州大学,有机化学专业,理学博士
2003-2007 西北大学,应用化学专业,理学学士
· 荣誉奖励
2023 Thieme与中国化学会有机合成新锐奖
· 研究兴趣
天然产物全合成以及合成导向的方法学研究
· 代表成果
1. Total Synthesis of (±)-Rubriflordilactone A. Zheng Xudong, Guo Xinlong, Wang Hongyu, Zhou Pan-Pan, Chen Xiaoming*. J. Am. Chem. Soc. 2024, 146, 7198-7203.
2. Enantiocontrolled Total Synthesis of (−)-Retigeranic Acid A. Chen Xiaoming*, Yao Weidong, Zheng Hufeng, Wang Hongyu, Zhou Pan-Pan, Zhu Dao- Yong, Wang Shao-Hua*. J. Am. Chem. Soc. 2023, 145, 13549-13555.
3. Asymmetric Total Synthesis of (+)-Alstonlarsine A. Yao Jun-Jun, Ding Rui, Chen Xiaoming, Zhai Hongbin*. J. Am. Chem. Soc. 2022, 144, 14396-14402.
4. Asymmetric Total Synthesis of (+)-Mannolide C. Ao Qiaoqiao, Zhang Hai-Jun, Zheng Jingbin, Chen Xiaoming*, Zhai Hongbin*. Angew. Chem. Int. Ed. 2021, 60, 21267-21271.
5. Au-Catalyzed 1,3-Acyloxy Migration/Cyclization Cascade: A Direct Strategy toward the Synthesis of Functionalized Abietane-Type Diterpenes. Tianlu Zheng, Sizhan Liu, Chen-Yu Huo, Jing Li, Bowen Wang, Daping Jin, Fu Cheng, Xiaoming Chen*, Xiaoming Zhang, Xuetao Xu, and Shaohua Wang*. CCS Chemistry 2020, 2, 2795-2802.
6. Divergent total syntheses of (-)-daphnilongeranin B and (-)-daphenylline. Xiaoming Chen#, Haijun Zhang#, Xinkan Yang, Houqiang Lv, Xiaoru Shao, Cheng Tao, Huifei Wang, Bin Cheng, Yun Li, Jingjing Guo, Jing Zhang, and Hongbin Zhai*. Angew. Chem. Int. Ed. 2018, 130, 959-963.(#contributed equally)
7. Trifunctionalization of Allenes via Cobalt-Catalyzed MHP-Assisted C−H Bond Functionalization and Molecular Oxygen Activation. Shengxian Zhai, Shuxian Qiu, Xiaoming Chen, Cheng Tao, Yun Li, Bin Cheng, Huifei Wang, and Hongbin Zhai*. ACS Catal. 2018, 8, 6645.
8. Formal Synthesis of (±)-Aplykurodinone-1 through a Hetero-Pauson–Khand Cycloaddition Approach. Cheng Tao, Jing Zhang, Xiaoming Chen, Huifei Wang, Yun Li, Bin Cheng, and Hongbin Zhai*. Org. Lett. 2017, 19, 1056.
9. 2-(1-Methylhydrazinyl)pyridine as a reductively removable directing group in a cobalt-catalyzed C(sp2)–H bond alkenylation/annulation cascade. Shengxian Zhai, Shuxian Qiu, Xiaoming Chen, Jiang Wu, Hua Zhao, Cheng Tao, Yun Li, Bin Cheng, Huifei Wang, and Hongbin Zhai*. Chem. Commun. 2017, 54, 98.
10. Total synthesis of (+)-gelsemine via an organocatalytic Diels-Alder approach. Xiaoming Chen, Shengguo Duan, Cheng Tao, Hongbin Zhai*, and Fayang G. Qiu*. Nat. Commun. 2015, 6, 7204.