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刘雪原

2019-01-10 08:59:00
刘雪原
刘雪原
博士、教授、硕士生导师
电话:
+86-931-8912500
邮箱:
liuxuey@lzu.edu.cn
· EDUCATION AND EXPERIMENCE

2016-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授

2009-2016           兰州大学化学化工学院、功能有机分子化学国家重点实验室,副教授

2006-2009           兰州大学化学化工学院、功能有机分子化学国家重点实验室,讲师

2001-2006           兰州大学(导师: 梁永民),理学博士

1991-1995           兰州大学,理学学士

荣誉奖励

2017                    Thieme Chemistry Journals Award

研究兴趣

过渡金属催化方法学研究及有机氟化物的合成

代表成果

1. Aryl-To-Vinyl 1,4-Nickel Migration/Reductive Cross-Coupling Reaction for The Stereoselective Synthesis of Multisubstituted Olefins. Cui-Tian Wang, Peng-Yu Liang, Ming Li, Bin Wang, Yu-Zhao Wang, Xue-Song Li, Wan-Xu Wei, Xue-Ya Gou, Ya-Nan Ding, Zhe Zhang, Yu-Ke Li, Xue-Yuan Liu*, and Yong-Min Liang*, Angew. Chem. Int. Ed. 2023, 62, e202304447.

2. Stereoselective Synthesis of Multisubstituted Alkenes via Ruthenium-Catalyzed Remote Migration Arylation of Nonactivated Olefins. Yu-Yong Luan, Jin-Ye Li, Xue-Ya Gou, Wei-Yu Shi, Tian Ding, Zhe Zhang, Xi Chen, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2023, 25, 5111.

3. Visible-Light-Mediated Synthesis of C‑Alkyl Glycosides via Glycosyl Radical Addition and Aryl Migration. Rui-Qiang Jiao, Ya-Nan Ding, Ming Li, Wei-Yu Shi, Xi Chen, Zhe Zhang, Wan-Xu Wei, Xue-Song Li, Xiao-Ping Gong, Yu-Yong Luan, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2023, 25, 6099.

4. Photoredox-Catalyzed N‑Directed Regioselective Difluoroalkylation of Unactivated C(Sp3)-H Bonds. Xi Chen, Zhe Zhang, Wei-Yu Shi, Ya-Nan Ding, Yu-Yong Luan, Yan-Chong Huang, Qiang Wang*, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2023, 25, 4456.

5. Visible-Light-Induced C-F and C-N Bond Cleavage for the Synthesis of gem-Difluoroalkenes. Bin Wang, Cui-Tian Wang, Xue-Song Li, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2022, 24, 6566.

6. Three-Component Ru-Catalyzed Regioselective Alkylarylation of Vinylarenes via Meta-Selective C(sp2)-H Bond Functionalization. Hong-Chao Liu, Xiao-Ping Gong, Yu-Zhao Wang, Zhi-Jie Niu, Heng Yue, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2022, 24, 3043.

7. Ortho C-H Hydroxyalkylation or Methylation of Aryl Iodides by Ethers and TMSI via a Catellani Strategy. Zhe Zhang, Xi Chen, Xue-Song Li, Cui-Tian Wang, Zhi-Jie Niu, Bo-Sheng Zhang, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2022, 24, 6897.

8. Ni-Catalyzed Remote Radical/Cross-Electrophile Coupling Cascade for Selective C(sp3)-H Arylation. Ya-Ting Wen, Xiang-Tao Kong, Hong-Chao Liu, Cui-Tian Wang, Wan-Xu Wei, Bin Wang, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2022, 24, 2399.

9. Enantioselective Synthesis of Both Axially and Planar Chiral Ferrocenes via Axial-to-Planar Diastereoinduction. Yang An, Xiao-Yan Zhang, Ya-Nan Ding, Yuke Li*, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett2022, 24, 7294.

10. Photo-Catalyzed Redox-Neutral 1,2-Dialkylation of Alkenes.Wen-Hui Sun, Jian-Yu Zou, Xiao-Jing Xu, Jin-Lin Wang, Mei-Ling Liu, and Xue-Yuan Liu*, Adv. Synth. Catal. 2022, 364, 2260.

11. Copper-Catalyzed Hydrogen Atom Transfer and Aryl Migration Strategy for the Arylalkylation of Activated Alkenes. Xi Chen, Qiang Wang, Zhe Zhang, Zhi-Jie Niu, Wei-Yu Shi, Xiao-Ping Gong, Rui-Qiang Jiao, Ming-Hui Gao, Xue-Yuan Liu*, and Yong-Min Liang*, Org. Lett. 2022, 24, 4338.

12. Copper-Catalyzed Aminoarylation of Alkenes via Aminyl Radical Addition and Aryl Migration Jin-Lin Wang, Mei-Ling Liu, Jian-Yu Zou, Wen-Hui Sun, and Xue-Yuan Liu*,Org. Lett., 2022,24,1309.

13. Copper-Catalyzed Amino Radical Tandem Cyclization Toward the Synthesis of Indolo-[2,1-a] Isoquinolines. Mei-Ling Liu, Jing-Ling Wang, Xue-Song Li, Wen-Hui Sun, and Xue-Yuan Liu*, Org. Chem. Front. 2022, 9, 2438.

14. Copper-Catalyzed Direct Allenylation of Inactive Cyclic Ethers. Yichuan Zhao, Jin-Lin Wang,Zhe Zhang, Xue-Song, LiZhi-Jie Niu, Xue-Yuan Liu*. J. Org. Chem. 2021, 86, 18056-18066.

15. Photoredox-Catalyzed Redox-Neutral Difluoroalkylation to Construct Perfluoroketones with Difluoroenoxysilanes. Jian-Yu Zou, Yu-Zhao Wang, Wen-Hui Sun, Wu-Jie Lin, Xue-Yuan Liu*. Org. Biomol. Chem. 202119, 8696-8700.

16. Preparation of Oxindoles via Visible-Light-Induced Amination/Cyclization of Arylacrylamides with Alkyl Amines. Yuzhao Wang, Wujie Lin, Jianyu Zou, Wei Yu*, and Xueyuan Liu*. Adv. Synth. Catal2020, 362, 3116-3120.

17. Construction of Boronated γ-Lactams via Palladium-Catalyzed Intramolecular Boryldifluoroalkylation of Alkenes. Wujie Lin, Yuzhao Wang, Jianyu Zou, Yichuan Zhao, Jinlin Wang, and Xueyuan Liu*.  Adv. Synth. Catal. 2020, 362,  5009–5013. 

18. Synthesis of Tetrasubstituted α,β-Unsaturated Aldehydes via Radical 1,4-Aryl Migration/Trifluoromethylthiolation Cascade Reaction of Aryl Propynyl Ethers. Chunhuan Guo, Daoqian Chen, Si Chen, and Xueyuan Liu*. Adv. Synth. Catal.  2017, 359, 2901-2906.

19. AgSCF3‑Mediated Oxidative Trifluoro-methythiolation of Alkynes with Dearomatization to Synthesize SCF3‑Substituted Spiro[4, 5]trienones. Dongpo Jin, Pin Gao, Daoqian Chen, Si Chen, Jia Wang, Xueyuan Liu*, and Yongmin Liang. Org. Lett. 2016, 18, 3486-3489.

20. A metal-free transformation of alkynes to carbonyls directed by remote OH group. Daoqian Chen, Chunhuan Guo, Hengrui Zhang, Dongpo Jin, Xuesong Li, Pin Gao, Xinxing Wu, Xueyuan Liu*, and Yongmin Liang. Green Chem. 2016, 18, 4176-4180.

21. Merging photoredox with copper catalysis: decarboxylative difluoroacetylation of α,β-unsaturated carboxylic acids with ICF2CO2Et. Hengrui Zhang, Daoqian Chen, Yaping Han, Yifeng Qiu, Dongpo Jin, and Xueyuan Liu*. Chem. Commun. 2016, 52, 11827- 11830.

22. Regioselective access to CF3S-substituted dihydrofurans from homopropargylic alcohols with trifluoromethanesulfenamide. Daoqian Chen, Pin Gao, Pingxin Zhou, Xianrong Song, Yifeng Qiu, Xueyuan Liu*, and Yongmin Liang. Chem. Commun. 2015, 51, 6637-6639.

23. Copper-Catalyzed One-Pot Trifluoromethylation/Aryl Migration/ Carbonyl Formation with Homopropargylic Alcohols. Pin Gao, Shen, Yongwen Shen, Ran Fang, Xinhua Hao, Zihang Qiu, Fan Yang, Xiaobiao Yan, Qiang Wang, Xiangjun Gong, Xueyuan Liu*, and Yongmin Liang*. Angew. Chem. Int. Ed. 2014, 53, 7629-7633.

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