张辅民
2014-至今 兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授
2009-2014 兰州大学化学化工学院、功能有机分子化学国家重点实验室,副教授
2004-2009 兰州大学化学化工学院、功能有机分子化学国家重点实验室,讲师
2001-2004 兰州大学化学化工学院、功能有机分子化学国家重点实验室,助教
2007-2008 美国梅奥医学院 (合作导师: Yuan-Ping Pang),博士后
2003-2006 兰州大学,理学博士
1998-2001 兰州大学,理学硕士
1992-1994 甘肃教育学院
•荣誉奖励
2016 国家自然科学二等奖(第三完成人)
2015 教育部自然科学一等奖(第三完成人)
2015 兰州大学大学生创新创业行动计划“优秀指导教师”
•研究兴趣
活性天然产物和药物的合成及其导向的新合成方法研究
•代表成果
1. NiH-Catalyzed Regio- and Enantioselective Hydroalkylation for the Synthesis of β- or γ-Branched Chiral Aromatic N-Heterocycles. Ju-Song Yang, Ka Lu, Chen-Xiao Li, Zu-Hang Zhao, Fu-Min Zhang*, Xiao-Ming Zhang, and Yong-Qiang Tu*, J. Am. Chem. Soc. 2023, 145, 22122.
2. Enantioselective Total Syntheses of Six Natural and Two Proposed Meroterpenoids from Psoralea Corylifolia. Xiao-Wei Chen, Zi-Chao Hou, Chi Chen, Ling-Hui Zhang, Meng-En Chen, and Fu-Min Zhang*, Chem. Sci. 2023, 14, 5699.
3. Chiral 1,2,3-Triazolium Salt Catalyzed Asymmetric Mono- and Dialkylation of 2,5-Diketopiperazines with the Construction of Ttrasubstituted Carbon Centers. Jusong Yang, Ka Lu, Chenxiao Li, Zuhang Zhao, Xiaoming Zhang, Fu-Min Zhang*, and Yong-Qiang Tu*, Angew. Chem. Int. Ed.2022, 61, e202114129.
4. Preparation of Thioamides from Alkyl Bromides, Nitriles, and Hydrogen Sulfide through a Thio-Ritter-type Reaction. Shi-Zhong Tang, Kai Xiang, Rui Ye, Meng-En Chen, Jian-Chang Yu, Zhi-Juan He, and Fu-Min Zhang*, Chem. Commun. 2022, 58, 11430.
5. Copper-Nitrene-Catalyzed Desymmetric Oxaziridination/1,2-Alkyl Rearrangement of 1,3-Diketones toward Bicyclic Lactams. Xue Han, Li-Xin Shan, Jin-Xin Zhu, Chang-Sheng Zhang, Xiao-Ming Zhang, Fu-Min Zhang*, Hong Wang, Yong-Qiang Tu*, Ming Yang, Wen-Shuo Zhang. Angew. Chem. Int. Ed. 2021, 60, 22688-22692.
6. The Organocatalytic Enantiodivergent Fluorination of Beta-Ketodiaryl-Phosphine Oxides for the Construction of Carbon-Fluorine Quaternary Stereocenters. Shaolei Xie, Zhi-Juan He,Ling-Hui Zhang, Bo-Lun Huang, Xiao-Wei Chen, Zong-Song Zhan, Fu-Min Zhang*, Chem. Commun. 2021, 57 , 2069-2072.
7. Recent Advances of Ritter Reaction and its Synthetic Applications. Meng-En Chen‡, Xiao-Wei Chen‡, Yue-Hong Hu‡, Rui Ye, Jian-Wei Lv, Baosheng Li*, Fu-Min Zhang*, Org. Chem. Front. 2021, 8, 4623-4664.
8. Collective Total Synthesis of Aspidofractinine Alkaloids through the Development of a Bischler–Napieralski/Semipinacol Rearrangement Reaction. Shuanghu Wang, Ruiqi Si, Qingbo Zhuang, Xiang Guo, Tian Ke, Xiaoming Zhang*, Fu-Min Zhang*, and Yong-Qiang Tu*. Angew. Chem. Int. Ed. 2020, 59, 21954-21958.
9. Transition-Metal-Free Site-Selective γ-C(sp2)-H Monoiodination of Arenes Directed by an Aliphatic Keto Group. Hongli Bian, Shizhong Tang, Mengen Chen, Xiaoming Zhang, Jianwei Lv, Xioawei Chen, Fengming Qi, Shiwu Chen*, and Fu-Min Zhang*. Org. Lett. 2020, 22, 5314.
10. Construction of Polyfunctionalized 6-5-5 Fused Tricyclic Carbocycles via One-Pot Sequential Semipinacol Rearrangement/Michael Addition/Henry Reaction. Fuping Zhu, Xiang Guo, Fu-Min Zhang*, Xiaoming Zhang, Hong Wang, and Yong-Qiang Tu*. Org. Lett. 2020, 22, 2076.
11. Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (‒)-morphine. Qing Zhang, Fu-Min Zhang*, Changsheng Zhang, Sizhan Liu, Jinmiao Tian, Shaohua Wang, Xiaoming Zhang, and Yong-Qiang Tu*. Nat. Commun. 2019, 10, 2507.
12. Transition-Metal-Free α-Arylation of Nitroketones with Diaryliodonium Salts for the Synthesis of Tertiary α-Aryl, α-Nitro Ketones. Yang An, Xiaoming Zhang, Zeyu Li, Wenhui Xiong, Rundong Yu, and Fu-Min Zhang*. Chem. Commun., 2019, 55, 119.
13. Catalytic asymmetric total syntheses of (−)-galanthamine and (−)-lycoramine. Qing Zhang, Fu-Min Zhang,* Changsheng Zhang, Sizhan Liu, Jinmiao Tian, Shaohua Wang, Xiaoming Zhang, and Yong-Qiang Tu*. J. Org. Chem. 2019, 84, 12664.
14. Comprehension of the α-arylation of nitroalkanes. Pengfei Zheng, Yang An, Zuoyi Jiao*, Zhoubao Shi, and Fu-Min Zhang*. Curr. Org. Chem. 2019, 23, 1560.
15. p-Toluenesulfonic Acid Catalysed Fluorination of α-Branched Ketones for the Construction of Fluorinated Quaternary Carbon Centres. Tang Shizhong, Bian Hongli, Zhan Zongsong, Chen Meng-En, Lv Jianwei, Xie Shaolei, and Zhang Fu-Min*. Chem. Commun. 2018, 54, 12377.
16. Recent Progress in the Isolation, Bioactivity, Biosynthesis, and Total Syntheses of Natural Spiroketals. Zhang Fu-Min, Zhang Shuyu, and Tu Yong-Qiang*. Nat. Prod. Rep. 2018, 35, 75-104.
17. Applications of Ammonium Bifluoride in Organic Synthesis. Li Jiasheng, Dong Weizhe, Lu Hui, and Zhang Fu-Min*. Curr. Org. Chem. 2018, 22, 581.
18. Copper-Assisted Direct Nitration of Cyclic Ketones with Ceric Ammonium Nitrate for the Synthesis of Tertiary α-Nitro-α-Substituted Scaffolds. Zhiqiang Zhang, Tao Chen, and Fu-Min Zhang*. Org. Lett. 2017, 19, 1124-1127.
19. A Simple and Efficient Method for the Preparation of α-Halogenated Ketones Using Iron(III) Chloride and Iron(III) Bromide as Halogen Sources with Phenyliodonium Diacetate as Oxidant. Shizhong Tang, Wenshuang Zhao,Tao Chen,Yang Liu,Xiaoming Zhang,and Fu-Min Zhang*. Adv. Synth. Catal. 2017, 359, 4177-4183.
20. A Cu-Mediated One-Pot Michael Addition/a-Arylation Strategy Using A Diaryliodonium Salt: A Direct and Efficient Approach to α-Aryl-β-Substituted Cyclic Ketone Scaffolds. Jinlong Pan, Tao Chen, Zhiqiang Zhang, Yifan Li, Xiaoming Zhang, and Fu-Min Zhang*. Chem. Commun. 2016, 52, 2382-2385.
21. NH4HF2 as A Selective TBS-Removal Reagent for the Synthesis of Highly Functionalized Spiroketal via Tandem Deprotection/Spiroketalization Procedure. Hui Lu, Fu-Min Zhang*, Jinlong Pan, Tao Chen, and Yifan Li. J. Org. Chem. 2014, 79, 546-558.
22. Towards the Real Didemnaketal A: Total Syntheses of Two C-21 Stereoisomers of the Proposed Didemnaketal A. Fu-Min Zhang*, and Yong-Qiang Tu. Tetrahedron Lett. 2014, 55, 3784-3787.
23. Total Synthesis of the Nominal Didemnaketal A. Zhang Fu-Min, Peng Lei, Li Hui, Ma Aijun, Peng Jinbao, Guo Jinging, Yang Dengtao, Hou Sihua, Tu Yong-Qiang*, Kitching William, Angew. Chem. Int. Ed. 2012, 51, 10846-10850.