李 亚
•教育背景
2002.09 -2005.07 中科院兰州化学物理研究所, 分析化学, 博士
1999.09 -2002.07 兰州大学, 有机化学, 硕士
1995.09 -1999.07 兰州大学, 应用化学, 学士
•工作经历
2009.05-至今 兰州大学, 功能有机分子化学国家重点实验室, 副教授
2005.07-2009.04 兰州大学, 功能有机分子化学国家重点实验室, 讲师
2017.01-2017.12 美国德州理工大学
2009.07-2010.07 美国密苏里大学
•研究兴趣
(1)天然化合物分子结构多样性的研究;
(2)中草药中具有生物活性的分子的发现及其作用机理的研究。
•代表成果
1. Chlorajaponins A–Q, lindenane-related sesquiterpenoid dimers from Chloranthus japonicus and their biological activities. Wei-Jiao Feng, Ya Li*, Kun Gao*, et al. Chin. J. Chem. 2024, 42, 1247-1259.
2. Abietane Diterpenoids with Anti-Inflammatory Activities from Callicarpa Bodinieri. Yue Sun, Hong-Ying Yang, Pei-Zhi Huang, Lan-Jun Zhang, Wei-Jiao Feng, Ya Li*, Kun Gao*, Phytochemistry, 2023, 214, 113825.
3. Isolation, Identification, and Activity Evaluation of Diterpenoid Alkaloids from Aconitum Sinomontanum. Ya Li*, Jun Zeng, Yu-hua Tian, Yanan Hou, Honghong Da, Jianguo Fang, Kun Gao*, Phytochemistry 2021, 190, 112880.
4. Phytotoxic neo-clerodane diterpenoids from the aerial parts of Scutellaria barbata. Hang-Ying Li, Ya Li⁎, Kun Gao⁎, et al. Phytochemistry 2020, 171, 112230. DOI: org/10.1016/j.phytochem.2019.112230.
5. Heliaquanoids A−E, five sesquiterpenoid dimers from Inula helianthus-aquatica. Zai-Qin Zheng, Ya Li*, Kun Gao*, et al. J. Org. Chem. 2019, 84, 4473−4477.
6. Highly oxygenated triterpenoids and rare tetraterpenoids from Abies chensiensis and their antibacterial activity. Wen-Jun Wei, Ya Li*, Kun Gao*, et al. J. Nat. Prod. 2019, 82, 10, 2859-2869.
7. Anti-inflammatory evaluation and structure-activity relationships of diterpenoids isolated from Euphorbia hylonoma. Wen-Jun Wei, Ya Li⁎, Kun Gao⁎, et al. Bioorganic Chemistry 2019, 93, 103256.
8. Chemical Structures of Lignans and Neolignans Isolated from Lauraceae. Ya Li*, Shuhan Xie, Jinchuan Ying, Wenjun Wei, and Kun Gao*. Molecules 2018, 23, 3164.
9.Phytotoxic ent-Isopimarane-Type Diterpenoids from Euphorbia hylonoma. Wenjun Wei, Qiuyan Song, Zaiqin Zheng, Xiaojun Yao, Ya Li*, and Kun Gao*. J. Nat. Prod. 2018, 81, 2381-2391.
10. Antifungal Activities of Isoflavonoids from Uromyces striatus Infected Alfalfa. Ya Li, Guangda Li, Hitao Yu, Xingzhi Jiao, and Kun Gao*. Chem. Biodivers. 2018, 15, e1800407.
11. Diterpenoids from Salvia miltiorrhiza and their immune-modulating activity. Wenjun Wei, Panpan Zhou, Changjun Lin, Weifeng Wang, Ya Li*, and Kun Gao*. J. Agr. Food Chem. 2017, 65, 5985−5993.
12. Aphapolins A and B: Two Nemoralisin Diterpenoids Isolated from Aphanamixis polystachya (Wall.) Fu-Hu Fang, Ya Li*, and Cheng-Shan Yuan*, et al. R. Parker. Eur. J. Org. Chem. 2017, 4429-4433. DOI: org/10.1002/ejoc.201700795.
13. Spirochensilides A and B, two new rearranged triterpenoids from Abies chensiensis. Qianqian Zhao, Qiuyan Song, Kan Jiang, Guangda Li, Wenjun Wei, Ya Li*, and Kun Gao*. Org. Lett. 2015, 17, 2760-2763.
•授权专利
1. 李亚,高坤,李航鹰,魏文君,陈建军. NEO-克罗烷型二萜类化合物对黑麦草的植物毒活性测试方法 专利号:ZL 201910594988.1
2. 李亚,袁呈山,高坤. 杜仲叶中综合提取桃叶珊瑚苷、绿原酸和杜仲胶的工艺 专利号:ZL 201810657908.8