Yueting Wu
2016-Present College of Chemistry and Chemical Engineering, Lanzhou University,
State Key Laboratory of Applied Organic Chemistry, associate professor
2015-2016 Center For Immunotherapy (CFI), Roswell Park Cancer Institute (RPCI),
Buffalo, NY, USA, postdoctoral researcher.
2009-2015 Department of Chemical Engineering, Department of Microbiology,
Immunology, & Cell Biology, West Virginia University, Morgantown,
WV, USA, Ph.D. graduate student.
2000-2006 College of Materials Science and Chemical Engineering, Zhejiang University,
Hangzhou, China. B.S. and M.S. graduate student, majoring in Biochemical
Engineering.
· Research Topics
Cancer immunotherapy and cancer immunology, cell-to-cell communication between cancer and immune cells. Nanosized biological particles (exosomes) isolated from cancer cells and/or immune cells. A variety of anti-cancer immunoregulating targets and their therapeutic effects, e.g. CTLA-4, PD1/PD-L1, LAG3.
· Publications
1. Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function. Yueting Wu, Wentao Deng, Emily Chambers McGinley, and David J. Klinke II*. Pigm.Cell Melanoma R. 2017, 30, 203-218.
2. Exosomes: improved methods to characterize their morphology, RNA content, and surface protein biomarkers. Yueting Wu, Wentao Deng, and David J. Klinke II*..Analyst 2015, 140, 6631-6642.
3. Interlocked positive and negative feedback network motifs regulate beta-catenin activity in the adherens junction pathway. David J. Klinke*, Nicholas Horvath, Vanessa Cuppett, Yueting Wu, Wentao Deng, and Rania Kanj. Mol. Biol.Cell 2015, 26, 3893-4181.
4. Inferring alterations in cell-to-cell communication in HER2+ breast cancer using secretome profiling of three cell models. David J. Klinke*, Nicholas Horvath, Vanessa Cuppett, Yueting Wu, Wentao Deng, and Rania Kanj. Biotechnol. Bioeng. 2014, 111, 1853-1863.
5. Selective filling of nanowells in nanowell arrays fabricated using polystyrene nanosphere lithography with cytochrome P450 enzymes. Lance A Wollenberg, John E Jett, Yueting Wu, Darcy R Flora, Nianqiang Wu, Timothy S Tracy, and Peter M Gannett. Nanotechnology 2012, 23, 385101.
6. Azathioprine hepatotoxicity and the protective effect of liquorice and glycyrrhizic acid. Yueting Wu, Chong Shen, Jian Yin, Jinpeng Yu, and Qin Meng*.Phytother Res. 2006, 20, 640-645.
7. Biodegradation of crude oil by Pseudomonas aeruginosa in the presence of rhamnolipids. Yueting Wu, Chong Shen, Jian Yin, Jinpeng Yu and Qin Meng*. 2005, 6, 725-730. (Indexed by EI, 2005).
