Xingang Xie
2012-Present College of chemistry and Chemical Engineering, Lanzhou University,
State Key Laboratory of Applied Organic Chemistry, Associated Professor
2010-2012 College of chemistry and Chemical Engineering, Lanzhou University,
State Key Laboratory of Applied Organic Chemistry, Lecturer
2006-2010 The Chinese University of Hong Kong (Advisor: Henry N. C. Wong),
postdoctoral associate
2001-2006 Lanzhou University (Advisor: Xuegong She and Xinfu Pan), D.Sc
1997-2001 Lanzhou University, B.Sc
· Honors and Rewards
2018 Thieme Chemistry Journal Award
2015 The First Prize in Natural Science of Gansu Province (Ranking 2/5)
· Research Topics
Our group is currently interested in the development of green and sustainable organic synthetic methodology, total synthesis of bioactive natural products and structure-activity-relationship (SAR) study.
· Publications
1. Concise Total Syntheses of Bioactive Alkaloids Enabled by Development or Application of Cascade Reactions: a Personnel Adventure. Xingang Xie, Xuegong She*, Chinese J. Chem. 2021, 39, 795-801.
2. Thiourea Catalyzed 1,6-Conjugate Addition of Indoles to Para-Quinone Methides. Guangmiao Wu, Tao Li, Fuhai Liu, Yulong Zhao, Shiqiang Ma, Shouchu Tang, Xingang Xie*, Xuegong She, Tetrahedron Lett. 2021, 81, 153315.
3. Enantioselective α‑Functionalization of 1,3-Dithianes by Iridium-Catalyzed Allylic Substitution. Panpan Wang, Qian Jiang, Ruibo Zhao, Xingang Xie*. Shouchu Tang*, and Xiaolei Wang*. J. Org. Chem. 2020, 85,12456-12467.
4. Visible Light Photoredox Catalyzed Deprotection of 1,3-Oxathiolanes. Mingyang Yang, Zhimin Xing, Bowen Fang, Xingang Xie,* and Xuegong She. Org. Biomol. Chem. 2020, 18, 288-291.
5. Total syntheses of (-)-15-oxopuupehenol and (+)-puupehenone and formal syntheses of (-)-puupehenol and (+)-puupehedione, Huayue Song, Lin Liu, Mingyang Yang, Guangmiao Wu, Peng Chen, Xingang Xie * and Xuegong She, Org. Chem. Front. 2020, 1, 35-42.
6. Synthetic studies towards daphniyunnine B: Construction of AC bicyclic skeleton with two vicinal all carbon quaternary stereocenters, Haiyu Sun, Guangmiao Wu and Xingang Xie*. Chinese Chem. Lett. 2019, 30, 1538-1540.
7. Concise formal synthesis of (+)-pyripyropene A. Tao Li, Guangmiao Wu, Shangbiao Feng, Xiaojun Hu, Weiwei Zhang, Shouchu Tang, Xingang Xie*, Xuegong She, Tetrahedron 2019, 75, 3939-3942.
8. Total synthesis of (-)-8-epi-chromazonarol enabled by a unique N2H4•H2O promoted intramolecular oxa-Michael cyclization reaction, Lin Liu, Huayue Song, Peng Chen, Ziyun Yuan, Shangbiao Feng, Weiwei Zhang, Bowen Fang, Xingang Xie*, Xuegong She. Org. Chem. Front. 2018, 5, 3013-3017.
9. Visible-light promoted dithioacetalization of aldehydes with thiols under aerobic and photocatalyst-free conditions, Zhimin Xing, Mingyang Yang, Haiyu Sun, Zemin Wang, Peng Chen, Lin Liu, Xiaolei Wang, Wang*, Xingang Xie*, Xuegong She. Green Chem. 2018, 20, 5117-5122.
10. A rapid construction of the ABC tricyclic skeleton of malabanone A, Tao Li, Guangmiao Wu, Shangbiao Feng, Zemin Wang, Xingang Xie*, Xuegong She. Org. Biomol. Chem. 2018, 16, 8491-8494.
11. Rapid construction of complex tetracyclic frameworks via a gold(I)-catalyzed tandem 1,2-acyloxy migration/[3 + 2] cycloaddition/Friedel–Crafts type cyclization reaction of linear enynyl esters. Haiyu Sun, Shiyan Xu, Zhimin Xing, Lin Liu, Shangbiao Feng, Bowen Fang, Xingang Xie*, and Xuegong She. Org. Chem. Front. 2017, 4, 2109-2113.
12. Rapid construction of the 6/6/5 tricyclic framework via a tandem radical cyclization reaction and its application to the synthesis of 5-epi-7-deoxy-isoabietenin A. Hao Zhang, Shiqiang Ma, Zhimin Xing, Lin Liu, Bowen Fang, Xingang Xie*, and Xuegong She*. Org. Chem. Front. 2017, 4, 2211–2215.
13. Visible-Light-Promoted Dual C−C Bond Formations of Alkynoates via a Domino Radical Addition/ Cyclization Reaction: A Synthesis of Coumarins. Shangbiao Feng, Xingang Xie*, Weiwei Zhang, Lin Liu, Zhuliang Zhong, Dengyu Xu, and Xuegong She.Org. Lett. 2016, 18, 3846−3849.
14. An Efficient Synthesis of Benzazocines by Gold(I)-Catalyzed Tandem 1,2-Acyloxy Shift/[3+2] Cycloaddition of Terminal 1,9-Enynyl Esters. Shangbiao Feng, Zhengshen Wang, Weiwei Zhang, Xingang Xie*, and Xuegong She. Chem.-Asian J. 2016, 11, 2167–2172.
15. Concise Total Synthesis of Isospongian Diterpenoid (±)-Polyrhaphin D. Zemin Wang, Zhimin Xing, Lin Liu, Hao Zhang, Zhuliang Zhong, Xingang Xie*, and Xuegong She. ChemistrySelect 2016, 1, 2225–2227.
16. Gold(I)-Catalyzed Tandem Reaction of γ-Amino-Substituted Propargylic Esters to Pyrrolines and its Application in the Formal Synthesis of (±)-Aphanorphine. Zhengshen Wang, Huaiji Zheng, Juan Yang, Xingang Xie*, and Xuegong She*. Adv. Synth. Catal. 2015, 357, 2082–2088.
17. Scalable, efficient total synthesis of (+)-mupirocin H. Changgui Zhao, Ziyun Yuan, Yuanyuan Zhang, Bin Ma, Huilin Li, Shouchu Tang, Xingang Xie* and Xuegong She*. Org. Chem. Front. 2014, 1, 105-108.
18. Enantioselective Total Synthesis of (−)-Walsucochin B. Shiyan Xu, Jixiang Gu, Huilin Li, Donghui Ma, Xingang Xie*, and Xuegong She. Org. Lett. 2014, 16, 1996-1999.
19. Concise Formal Syntheses of the Amaryllidaceae Alkaloids (±)-Tazettine and (±)-6a-Epi- pretazettine: Construction of the Core Skeleton via Tandem Intramolecular Oxidative Friedel– Crafts / Aza-Michael Reaction. Donghui Ma, Changgui Zhao, Huilin Li, Jing Qi, Ling Zhang, Shiyan Xu, Xingang Xie*, and Xuegong She*. Chem.-Asian. J. 2013, 8, 364-368.
20. Concise Enantioselective Synthesis of Cephalosporolide B, (4R)-4-OMe-Cephalo- sporolide C, and (4S)-4-OMe Cephalosporolide C. Bin Ma, Zhuliang Zhong, Haitao Hu, Huilin Li, Changgui Zhao, Xingang Xie*, and Xuegong She*. Chem.-Asian. J. 2013, 8, 1391-1394.
21. Tandem Oxidative Dearomatization/Intramolecular Diels-Alder Reaction for Construction of the Tricyclic Core of Palhinine A. Changgui Zhao, Huaiji Zheng, Peng Jing, Bowen Fang, Xingang Xie*, and Xuegong She*. Org. Lett. 2012, 14, 2293-2295.
22. Total Synthesis of (±)-Kopsihainanine A. Masaya Mizutani, Shigeo Yasuda, and Chisato Mukai*. Chem.-Eur. J. 2012, 18, 6729-6732.
23. Rapid Construction of the [6-6-6-5] Tetracyclic Skeleton of the Daphniphyllum Alkaloid Daphenylline. Huilin Li, Jiyue Zheng, Shiyan Xu, Donghui Ma, Changgui Zhao, Bowen Fang, Xingang Xie*，and Xuegong She*. Chem.-Asian. J. 2012, 7, 2519-2522.
